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KMID : 0388220080150010070
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Journal of the Korean Rheumatism Association
2008 Volume.15 No. 1 p.70 ~ p.75
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A Case of Bronchioloalveolar Carcinoma Presenting Adult-onset Still’s Disease-like Manifestations due to Paraneoplastic Syndrome
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Kim Hyun-Jin
Cho Chul-Soo
Kwok Seung-Ki
Shin Jung-Ha
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Abstract
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Adult-onset Still’s disease (AOSD) is a systemic inflammatory disorder with the characteristics of high spiking fever, evanescent salmon-colored skin rash, arthralgia or arthritis, lymphadenopathy, hepato-splenomegaly, sore throat, leukocytosis, negative autoantibody and hyperferritinemia. There are reports that rheumatic diseases such as dermatomyositis, polymyositis, hypertrophic osteoarthropathy, and polymyalgia rheumatica are associated with neoplasms. And small cell lung cancer, thymoma, lymphoma, leukemia, and breast cancer are known to be more associated with paraneoplastic syndromes mimicking rheumatic diseases. We experienced a case with bronchioloalveolar carcinoma who developed clinical manifestations of AOSD. Although there are several reports that AOSD is associated with paraneoplastic syndrome, to our knowledge, this is the first case of bronchioloalveolar carcinoma mimicking AOSD reported in the world.
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KEYWORD
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Adult-onset Still’s disease, Bronchioloalveolar carcinoma, Paraneoplastic syndrome
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